The Binding of Isaac Wiki

Contagion

Contagion

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The first enemy killed in a room explodes and poisons nearby enemies. Poisoned enemies will also explode upon death.

Quote

"Outbreak!"

Effects

  • In each room, the first enemy killed will release a gas explosion and poison nearby enemies.
    • Poisoned enemies will also release gas upon death, spreading the effect.
      • Poisoned enemies do not need to die while the poison is still active to spread the effect.
    • The effect will also activate if a shopkeeper is destroyed before killing any enemies.
      • Re-entering a room and destroying another shopkeeper inside it will trigger the effect for the second time.

Found in

  • Treasure Room
  • Treasure Room (Greed Mode)
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