#413 ยท Passive Item

Immaculate Conception

"Feed them love"

  • Upon picking up enough heart pickups, Isaac gains a permanent angelic familiar and generates a soul heart drop. Possible familiars include:
  • The first and second familiars will spawn after picking up 15 heart pickups each. The third, fourth, and fifth familiars will spawn after picking up 30 heart pickups each. No further familiars will spawn.
Unlock

Complete the Boss Rush as Lilith

Found in

  • Angel Room
  • Angel Room (Greed Mode)

Video