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#413 ยท
Passive Item
Immaculate Conception
"Feed them love"
Wiki Page
Upon picking up enough heart pickups, Isaac gains a permanent angelic familiar and generates a soul heart drop. Possible familiars include:
Holy Water
Guardian Angel
Sworn Protector
The Relic
Seraphim
The first and second familiars will spawn after picking up 15 heart pickups each. The third, fourth, and fifth familiars will spawn after picking up 30 heart pickups each. No further familiars will spawn.
Unlock
Complete the Boss Rush as Lilith
Found in
Angel Room
Angel Room (Greed Mode)
Video