- Coins have a 10% chance to be replaced with Grab Bags. Bombs, Keys, Cards, Runes, and Lil' Batteries have a 20% chance.
- This includes pickups spawned by most sources: room rewards, chests, slot machines, special shopkeepers, etc.
- The exception to this are pickups spawned by Isaac himself directly, e.g. with the likes of or , and contents of other sacks.
- Spawns a sack upon pickup.
Found in
- Secret Room
- Shop