Using an active item will drop it onto a pedestal on the ground. Taking damage may result in dropping a passive item.
Quote
"Can't hold it!"
Effects
- Using an active item will drop it onto a pedestal on the ground.
- This does not apply to permanent active items, which are located in the pill/card slot.
- When Isaac takes damage, there is a 2% chance one of Isaac's passive items will drop on the ground.